Potassium in PDB 7sit: Crystal Structure of Voltage Gated Potassium Ion Channel, Kv 1.2 Chimera-3M

The structure of Crystal Structure of Voltage Gated Potassium Ion Channel, Kv 1.2 Chimera-3M, PDB code: 7sit was solved by R.Reddi, K.Matulef, E.A.Riederer, M.R.Whorton, F.I.Valiyaveetil, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.16 / 3.32
Space group	P 4 21 2
Cell size a, b, c (Å), α, β, γ (°)	129.587, 129.587, 278.482, 90, 90, 90
R / Rfree (%)	25.1 / 28.9

The binding sites of Potassium atom in the Crystal Structure of Voltage Gated Potassium Ion Channel, Kv 1.2 Chimera-3M (pdb code 7sit). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 4 binding sites of Potassium where determined in the Crystal Structure of Voltage Gated Potassium Ion Channel, Kv 1.2 Chimera-3M, PDB code: 7sit:
Jump to Potassium binding site number: 1; 2; 3; 4;

Potassium binding site 1 out of 4 in the Crystal Structure of Voltage Gated Potassium Ion Channel, Kv 1.2 Chimera-3M


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Crystal Structure of Voltage Gated Potassium Ion Channel, Kv 1.2 Chimera-3M within 5.0Å range: probe atom residue distance (Å) B Occ B:K501 b:118.9 occ:0.25 O B:THR370 2.8 126.0 1.0 OG1 B:THR370 3.0 117.0 1.0 K B:K502 3.6 122.7 0.2 CB B:THR370 3.7 115.5 1.0 C B:THR370 3.9 122.8 1.0 CA B:THR370 4.4 117.9 1.0 O B:THR369 4.7 111.4 1.0 CG2 B:THR370 4.9 120.3 1.0 N B:VAL371 5.0 120.6 1.0

Potassium binding site 2 out of 4 in the Crystal Structure of Voltage Gated Potassium Ion Channel, Kv 1.2 Chimera-3M


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Crystal Structure of Voltage Gated Potassium Ion Channel, Kv 1.2 Chimera-3M within 5.0Å range: probe atom residue distance (Å) B Occ B:K502 b:122.7 occ:0.25 O B:VAL371 2.8 127.1 1.0 O B:THR370 2.9 126.0 1.0 C B:VAL371 3.4 120.7 1.0 K B:K501 3.6 118.9 0.2 C B:THR370 3.8 122.8 1.0 CA B:VAL371 3.9 115.7 1.0 N B:VAL371 4.3 120.6 1.0 N B:GLY372 4.3 121.3 1.0 CA B:GLY372 4.7 126.3 1.0 CA B:THR370 5.0 117.9 1.0

Potassium binding site 3 out of 4 in the Crystal Structure of Voltage Gated Potassium Ion Channel, Kv 1.2 Chimera-3M


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Crystal Structure of Voltage Gated Potassium Ion Channel, Kv 1.2 Chimera-3M within 5.0Å range: probe atom residue distance (Å) B Occ D:K501 b:160.0 occ:0.25 O D:THR370 2.8 163.1 1.0 O D:VAL371 2.8 166.5 1.0 C D:VAL371 3.4 161.6 1.0 CA D:VAL371 3.7 162.3 1.0 C D:THR370 3.7 165.3 1.0 K D:K502 3.8 158.9 0.2 N D:VAL371 4.1 167.3 1.0 N D:GLY372 4.4 160.7 1.0 CA D:GLY372 4.9 168.9 1.0 CA D:THR370 4.9 162.2 1.0

Potassium binding site 4 out of 4 in the Crystal Structure of Voltage Gated Potassium Ion Channel, Kv 1.2 Chimera-3M


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 4 of Crystal Structure of Voltage Gated Potassium Ion Channel, Kv 1.2 Chimera-3M within 5.0Å range: probe atom residue distance (Å) B Occ D:K502 b:158.9 occ:0.25 O D:THR370 2.9 163.1 1.0 OG1 D:THR370 3.0 172.1 1.0 CB D:THR370 3.7 163.5 1.0 K D:K501 3.8 160.0 0.2 C D:THR370 3.9 165.3 1.0 CA D:THR370 4.5 162.2 1.0 O D:THR369 4.8 160.4 1.0 CG2 D:THR370 4.9 163.2 1.0

R.Reddi, K.Matulef, E.A.Riederer, M.R.Whorton, F.I.Valiyaveetil. Structural Basis For C-Type Inactivation in A Shaker Family Voltage-Gated K + Channel. Sci Adv V. 8 M8804 2022.
ISSN: ESSN 2375-2548
PubMed: 35452285
DOI: 10.1126/SCIADV.ABM8804