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Potassium in PDB 7r43: Bovine Complex I in the Presence of IM1761092, Active Class III (Composite Map)

Enzymatic activity of Bovine Complex I in the Presence of IM1761092, Active Class III (Composite Map)

All present enzymatic activity of Bovine Complex I in the Presence of IM1761092, Active Class III (Composite Map):
1.6.5.3; 1.6.99.3; 7.1.1.2;

Other elements in 7r43:

The structure of Bovine Complex I in the Presence of IM1761092, Active Class III (Composite Map) also contains other interesting chemical elements:

Zinc (Zn) 1 atom
Iron (Fe) 28 atoms
Magnesium (Mg) 1 atom

Potassium Binding Sites:

The binding sites of Potassium atom in the Bovine Complex I in the Presence of IM1761092, Active Class III (Composite Map) (pdb code 7r43). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total only one binding site of Potassium was determined in the Bovine Complex I in the Presence of IM1761092, Active Class III (Composite Map), PDB code: 7r43:

Potassium binding site 1 out of 1 in 7r43

Go back to Potassium Binding Sites List in 7r43
Potassium binding site 1 out of 1 in the Bovine Complex I in the Presence of IM1761092, Active Class III (Composite Map)


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Bovine Complex I in the Presence of IM1761092, Active Class III (Composite Map) within 5.0Å range:
probe atom residue distance (Å) B Occ
G:K804

b:32.0
occ:1.00
O G:LEU208 2.7 32.2 1.0
O G:ILE200 2.8 34.3 1.0
OE1 G:GLN110 2.8 29.7 1.0
O G:VAL205 2.9 29.2 1.0
O G:HOH953 3.1 32.0 1.0
O G:CYS203 3.1 31.2 1.0
CD G:GLN110 3.6 29.7 1.0
C G:ILE200 3.9 34.3 1.0
CB G:CYS203 3.9 31.2 1.0
NE2 G:GLN110 3.9 29.7 1.0
CE Q:MET45 4.0 33.6 1.0
C G:LEU208 4.0 32.2 1.0
C G:VAL205 4.0 29.2 1.0
C G:CYS203 4.1 31.2 1.0
CG2 G:ILE200 4.2 34.3 1.0
SG G:CYS203 4.4 31.2 1.0
CA G:ILE200 4.4 34.3 1.0
CG2 G:THR209 4.4 33.0 1.0
CA G:CYS203 4.5 31.2 1.0
CA G:GLY206 4.6 29.8 1.0
N G:VAL205 4.7 29.2 1.0
N G:GLY206 4.8 29.8 1.0
N G:LEU208 4.8 32.2 1.0
N G:CYS203 4.8 31.2 1.0
CA G:LEU208 4.9 32.2 1.0
CA G:THR209 4.9 33.0 1.0
N G:THR209 4.9 33.0 1.0
CG G:GLN110 4.9 29.7 1.0
CB G:ILE200 4.9 34.3 1.0
CA G:VAL205 5.0 29.2 1.0
N G:ASP201 5.0 35.5 1.0

Reference:

H.R.Bridges, J.N.Blaza, Z.Yin, I.Chung, M.N.Pollak, J.Hirst. Structural Basis of Mammalian Respiratory Complex I Inhibition By Medicinal Biguanides. Science V. 379 351 2023.
ISSN: ESSN 1095-9203
PubMed: 36701435
DOI: 10.1126/SCIENCE.ADE3332
Page generated: Mon Aug 12 20:52:06 2024

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