Potassium in PDB 7pxg: Verruculogen-Bound Drosophila Slo Channel
Other elements in 7pxg:
The structure of Verruculogen-Bound Drosophila Slo Channel also contains other interesting chemical elements:
Potassium Binding Sites:
The binding sites of Potassium atom in the Verruculogen-Bound Drosophila Slo Channel
(pdb code 7pxg). This binding sites where shown within
5.0 Angstroms radius around Potassium atom.
In total 4 binding sites of Potassium where determined in the
Verruculogen-Bound Drosophila Slo Channel, PDB code: 7pxg:
Jump to Potassium binding site number:
1;
2;
3;
4;
Potassium binding site 1 out
of 4 in 7pxg
Go back to
Potassium Binding Sites List in 7pxg
Potassium binding site 1 out
of 4 in the Verruculogen-Bound Drosophila Slo Channel
Mono view
Stereo pair view
|
A full contact list of Potassium with other atoms in the K binding
site number 1 of Verruculogen-Bound Drosophila Slo Channel within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:K2007
b:36.2
occ:0.25
|
O
|
A:GLY303
|
2.9
|
42.0
|
1.0
|
O
|
D:GLY303
|
2.9
|
41.2
|
1.0
|
O
|
B:GLY303
|
2.9
|
41.1
|
1.0
|
O
|
C:TYR304
|
2.9
|
45.4
|
1.0
|
O
|
C:GLY303
|
3.1
|
41.1
|
1.0
|
O
|
B:TYR304
|
3.1
|
45.3
|
1.0
|
O
|
D:TYR304
|
3.2
|
45.5
|
1.0
|
O
|
A:TYR304
|
3.3
|
45.9
|
1.0
|
K
|
A:K2008
|
3.5
|
34.7
|
0.5
|
C
|
C:TYR304
|
3.6
|
45.4
|
1.0
|
C
|
B:TYR304
|
3.7
|
45.3
|
1.0
|
C
|
D:TYR304
|
3.8
|
45.5
|
1.0
|
C
|
A:TYR304
|
3.8
|
45.9
|
1.0
|
C
|
A:GLY303
|
4.0
|
42.0
|
1.0
|
C
|
B:GLY303
|
4.1
|
41.1
|
1.0
|
C
|
D:GLY303
|
4.1
|
41.2
|
1.0
|
C
|
C:GLY303
|
4.2
|
41.1
|
1.0
|
CA
|
C:TYR304
|
4.2
|
45.4
|
1.0
|
CA
|
B:TYR304
|
4.3
|
45.3
|
1.0
|
CA
|
D:TYR304
|
4.4
|
45.5
|
1.0
|
CA
|
A:TYR304
|
4.4
|
45.9
|
1.0
|
N
|
D:GLY305
|
4.4
|
49.1
|
1.0
|
N
|
C:GLY305
|
4.4
|
50.1
|
1.0
|
N
|
B:GLY305
|
4.5
|
47.9
|
1.0
|
N
|
A:GLY305
|
4.5
|
48.1
|
1.0
|
CA
|
D:GLY305
|
4.7
|
49.1
|
1.0
|
N
|
B:TYR304
|
4.7
|
45.3
|
1.0
|
N
|
D:TYR304
|
4.7
|
45.5
|
1.0
|
N
|
A:TYR304
|
4.7
|
45.9
|
1.0
|
N
|
C:TYR304
|
4.7
|
45.4
|
1.0
|
CA
|
C:GLY305
|
4.7
|
50.1
|
1.0
|
CA
|
A:GLY305
|
4.7
|
48.1
|
1.0
|
CA
|
B:GLY305
|
4.8
|
47.9
|
1.0
|
|
Potassium binding site 2 out
of 4 in 7pxg
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Potassium Binding Sites List in 7pxg
Potassium binding site 2 out
of 4 in the Verruculogen-Bound Drosophila Slo Channel
Mono view
Stereo pair view
|
A full contact list of Potassium with other atoms in the K binding
site number 2 of Verruculogen-Bound Drosophila Slo Channel within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:K2008
b:34.7
occ:0.50
|
O
|
C:GLY303
|
2.7
|
41.1
|
1.0
|
O
|
B:VAL302
|
2.7
|
40.6
|
1.0
|
O
|
D:GLY303
|
2.8
|
41.2
|
1.0
|
O
|
D:VAL302
|
2.8
|
41.2
|
1.0
|
O
|
A:VAL302
|
2.8
|
40.8
|
1.0
|
O
|
C:VAL302
|
2.8
|
39.8
|
1.0
|
O
|
A:GLY303
|
2.8
|
42.0
|
1.0
|
O
|
B:GLY303
|
2.9
|
41.1
|
1.0
|
K
|
A:K2009
|
2.9
|
34.6
|
0.5
|
K
|
A:K2007
|
3.5
|
36.2
|
0.2
|
C
|
D:GLY303
|
3.6
|
41.2
|
1.0
|
C
|
C:GLY303
|
3.6
|
41.1
|
1.0
|
C
|
A:GLY303
|
3.7
|
42.0
|
1.0
|
C
|
B:GLY303
|
3.7
|
41.1
|
1.0
|
C
|
D:VAL302
|
3.8
|
41.2
|
1.0
|
C
|
A:VAL302
|
3.8
|
40.8
|
1.0
|
CA
|
D:GLY303
|
3.9
|
41.2
|
1.0
|
C
|
B:VAL302
|
3.9
|
40.6
|
1.0
|
CA
|
A:GLY303
|
3.9
|
42.0
|
1.0
|
C
|
C:VAL302
|
3.9
|
39.8
|
1.0
|
CA
|
B:GLY303
|
4.0
|
41.1
|
1.0
|
CA
|
C:GLY303
|
4.1
|
41.1
|
1.0
|
N
|
D:GLY303
|
4.3
|
41.2
|
1.0
|
N
|
A:GLY303
|
4.3
|
42.0
|
1.0
|
N
|
B:GLY303
|
4.4
|
41.1
|
1.0
|
N
|
C:GLY303
|
4.5
|
41.1
|
1.0
|
N
|
C:TYR304
|
4.7
|
45.4
|
1.0
|
N
|
D:TYR304
|
4.8
|
45.5
|
1.0
|
N
|
B:TYR304
|
4.8
|
45.3
|
1.0
|
N
|
A:TYR304
|
4.8
|
45.9
|
1.0
|
|
Potassium binding site 3 out
of 4 in 7pxg
Go back to
Potassium Binding Sites List in 7pxg
Potassium binding site 3 out
of 4 in the Verruculogen-Bound Drosophila Slo Channel
Mono view
Stereo pair view
|
A full contact list of Potassium with other atoms in the K binding
site number 3 of Verruculogen-Bound Drosophila Slo Channel within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:K2009
b:34.6
occ:0.50
|
O
|
C:VAL302
|
2.8
|
39.8
|
1.0
|
O
|
D:THR301
|
2.8
|
45.0
|
1.0
|
O
|
A:THR301
|
2.8
|
45.0
|
1.0
|
O
|
B:THR301
|
2.9
|
44.3
|
1.0
|
K
|
A:K2008
|
2.9
|
34.7
|
0.5
|
O
|
B:VAL302
|
3.0
|
40.6
|
1.0
|
O
|
D:VAL302
|
3.0
|
41.2
|
1.0
|
O
|
C:THR301
|
3.0
|
44.0
|
1.0
|
O
|
A:VAL302
|
3.1
|
40.8
|
1.0
|
C
|
C:VAL302
|
3.6
|
39.8
|
1.0
|
K
|
A:K2010
|
3.6
|
37.9
|
0.5
|
C
|
D:VAL302
|
3.7
|
41.2
|
1.0
|
C
|
B:VAL302
|
3.7
|
40.6
|
1.0
|
C
|
A:VAL302
|
3.8
|
40.8
|
1.0
|
C
|
D:THR301
|
3.9
|
45.0
|
1.0
|
C
|
A:THR301
|
3.9
|
45.0
|
1.0
|
C
|
B:THR301
|
3.9
|
44.3
|
1.0
|
CA
|
C:VAL302
|
4.1
|
39.8
|
1.0
|
CA
|
B:VAL302
|
4.1
|
40.6
|
1.0
|
C
|
C:THR301
|
4.1
|
44.0
|
1.0
|
CA
|
D:VAL302
|
4.1
|
41.2
|
1.0
|
CA
|
A:VAL302
|
4.2
|
40.8
|
1.0
|
N
|
D:VAL302
|
4.5
|
41.2
|
1.0
|
N
|
B:VAL302
|
4.5
|
40.6
|
1.0
|
N
|
A:VAL302
|
4.5
|
40.8
|
1.0
|
N
|
D:GLY303
|
4.5
|
41.2
|
1.0
|
N
|
C:GLY303
|
4.6
|
41.1
|
1.0
|
N
|
C:VAL302
|
4.6
|
39.8
|
1.0
|
N
|
B:GLY303
|
4.6
|
41.1
|
1.0
|
N
|
A:GLY303
|
4.7
|
42.0
|
1.0
|
CA
|
D:GLY303
|
4.9
|
41.2
|
1.0
|
CA
|
C:GLY303
|
4.9
|
41.1
|
1.0
|
O
|
C:GLY303
|
4.9
|
41.1
|
1.0
|
CA
|
D:THR301
|
5.0
|
45.0
|
1.0
|
CA
|
A:GLY303
|
5.0
|
42.0
|
1.0
|
CA
|
B:GLY303
|
5.0
|
41.1
|
1.0
|
CA
|
A:THR301
|
5.0
|
45.0
|
1.0
|
|
Potassium binding site 4 out
of 4 in 7pxg
Go back to
Potassium Binding Sites List in 7pxg
Potassium binding site 4 out
of 4 in the Verruculogen-Bound Drosophila Slo Channel
Mono view
Stereo pair view
|
A full contact list of Potassium with other atoms in the K binding
site number 4 of Verruculogen-Bound Drosophila Slo Channel within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:K2010
b:37.9
occ:0.50
|
O
|
C:THR301
|
2.9
|
44.0
|
1.0
|
O
|
D:THR301
|
3.0
|
45.0
|
1.0
|
OG1
|
A:THR301
|
3.0
|
45.0
|
1.0
|
O
|
A:THR301
|
3.0
|
45.0
|
1.0
|
OG1
|
D:THR301
|
3.1
|
45.0
|
1.0
|
O
|
B:THR301
|
3.1
|
44.3
|
1.0
|
OG1
|
B:THR301
|
3.2
|
44.3
|
1.0
|
OG1
|
C:THR301
|
3.2
|
44.0
|
1.0
|
CB
|
A:THR301
|
3.4
|
45.0
|
1.0
|
CB
|
D:THR301
|
3.5
|
45.0
|
1.0
|
K
|
A:K2009
|
3.6
|
34.6
|
0.5
|
CB
|
C:THR301
|
3.7
|
44.0
|
1.0
|
CB
|
B:THR301
|
3.7
|
44.3
|
1.0
|
C
|
C:THR301
|
3.9
|
44.0
|
1.0
|
C
|
D:THR301
|
4.0
|
45.0
|
1.0
|
C
|
A:THR301
|
4.0
|
45.0
|
1.0
|
C
|
B:THR301
|
4.1
|
44.3
|
1.0
|
CA
|
A:THR301
|
4.4
|
45.0
|
1.0
|
CA
|
D:THR301
|
4.4
|
45.0
|
1.0
|
CA
|
C:THR301
|
4.5
|
44.0
|
1.0
|
CA
|
B:THR301
|
4.6
|
44.3
|
1.0
|
CG2
|
A:THR301
|
4.6
|
45.0
|
1.0
|
CG2
|
D:THR301
|
4.7
|
45.0
|
1.0
|
CG2
|
B:THR301
|
4.9
|
44.3
|
1.0
|
CG2
|
C:THR301
|
4.9
|
44.0
|
1.0
|
N
|
C:VAL302
|
5.0
|
39.8
|
1.0
|
|
Reference:
T.Raisch,
A.Brockmann,
U.Ebbinghaus-Kintscher,
J.Freigang,
O.Gutbrod,
J.Kubicek,
B.Maertens,
O.Hofnagel,
S.Raunser.
Small Molecule Modulation of the Drosophila Slo Channel Elucidated By Cryo-Em To Be Published.
DOI: 10.1038/S41467-021-27435-W
Page generated: Mon Aug 12 19:59:38 2024
|