Potassium in PDB 7jku: Crystal Structure of A Four-Tetrad, Parallel, and K+ Stabilized Tetrahymena Thermophila Telomeric G-Quadruplex

The structure of Crystal Structure of A Four-Tetrad, Parallel, and K+ Stabilized Tetrahymena Thermophila Telomeric G-Quadruplex, PDB code: 7jku was solved by L.A.Yatsunyk, S.E.Mccarthy, D.Beseiso, E.P.Gallagher, E.V.Chen, J.Miao, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	32.60 / 1.97
Space group	P 2 21 21
Cell size a, b, c (Å), α, β, γ (°)	32.042, 39.11, 59.02, 90, 90, 90
R / Rfree (%)	24.7 / 26.2

The binding sites of Potassium atom in the Crystal Structure of A Four-Tetrad, Parallel, and K+ Stabilized Tetrahymena Thermophila Telomeric G-Quadruplex (pdb code 7jku). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 4 binding sites of Potassium where determined in the Crystal Structure of A Four-Tetrad, Parallel, and K+ Stabilized Tetrahymena Thermophila Telomeric G-Quadruplex, PDB code: 7jku:
Jump to Potassium binding site number: 1; 2; 3; 4;

Potassium binding site 1 out of 4 in the Crystal Structure of A Four-Tetrad, Parallel, and K+ Stabilized Tetrahymena Thermophila Telomeric G-Quadruplex


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Crystal Structure of A Four-Tetrad, Parallel, and K+ Stabilized Tetrahymena Thermophila Telomeric G-Quadruplex within 5.0Å range: probe atom residue distance (Å) B Occ A:K101 b:47.3 occ:0.50 O6 A:DG22 2.6 40.8 1.0 O6 A:DG16 2.7 47.0 1.0 O6 A:DG10 2.7 43.0 1.0 O6 A:DG4 2.8 42.2 1.0 K A:K102 3.2 54.5 1.0 C6 A:DG22 3.5 60.1 1.0 C6 A:DG16 3.6 56.0 1.0 C6 A:DG10 3.6 57.4 1.0 C6 A:DG4 3.7 54.4 1.0 N1 A:DG16 3.8 55.7 1.0 N1 A:DG22 3.9 50.5 1.0 N1 A:DG10 4.0 43.6 1.0 N1 A:DG4 4.0 54.2 1.0 C5 A:DG22 4.7 54.7 1.0 C5 A:DG16 4.8 47.8 1.0 C5 A:DG10 4.9 56.1 1.0 C5 A:DG4 4.9 57.8 1.0

Potassium binding site 2 out of 4 in the Crystal Structure of A Four-Tetrad, Parallel, and K+ Stabilized Tetrahymena Thermophila Telomeric G-Quadruplex


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Crystal Structure of A Four-Tetrad, Parallel, and K+ Stabilized Tetrahymena Thermophila Telomeric G-Quadruplex within 5.0Å range: probe atom residue distance (Å) B Occ A:K102 b:54.5 occ:1.00 O6 A:DG4 2.6 42.2 1.0 O6 A:DG10 2.6 43.0 1.0 O6 A:DG5 2.7 44.1 1.0 O6 A:DG23 2.7 55.9 1.0 O6 A:DG22 2.7 40.8 1.0 O6 A:DG11 2.8 50.1 1.0 O6 A:DG17 2.8 47.0 1.0 O6 A:DG16 2.9 47.0 1.0 K A:K101 3.2 47.3 0.5 K A:K103 3.3 56.3 1.0 C6 A:DG5 3.4 62.1 1.0 C6 A:DG4 3.4 54.4 1.0 C6 A:DG10 3.5 57.4 1.0 N1 A:DG5 3.6 51.5 1.0 C6 A:DG23 3.6 52.5 1.0 C6 A:DG11 3.6 64.1 1.0 C6 A:DG22 3.6 60.1 1.0 C6 A:DG17 3.7 59.0 1.0 N1 A:DG4 3.8 54.2 1.0 C6 A:DG16 3.8 56.0 1.0 N1 A:DG23 3.8 54.5 1.0 N1 A:DG22 3.9 50.5 1.0 N1 A:DG10 3.9 43.6 1.0 N1 A:DG11 3.9 51.0 1.0 N1 A:DG17 4.0 54.4 1.0 N1 A:DG16 4.1 55.7 1.0 C5 A:DG5 4.6 57.8 1.0 C5 A:DG4 4.7 57.8 1.0 C5 A:DG10 4.7 56.1 1.0 C5 A:DG11 4.8 54.1 1.0 C2 A:DG5 4.8 65.0 1.0 C5 A:DG23 4.8 56.8 1.0 C5 A:DG22 4.8 54.7 1.0 C5 A:DG17 4.8 59.4 1.0

Potassium binding site 3 out of 4 in the Crystal Structure of A Four-Tetrad, Parallel, and K+ Stabilized Tetrahymena Thermophila Telomeric G-Quadruplex


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Crystal Structure of A Four-Tetrad, Parallel, and K+ Stabilized Tetrahymena Thermophila Telomeric G-Quadruplex within 5.0Å range: probe atom residue distance (Å) B Occ A:K103 b:56.3 occ:1.00 O6 A:DG18 2.6 51.9 1.0 O6 A:DG6 2.6 55.0 1.0 O6 A:DG5 2.6 44.1 1.0 O6 A:DG11 2.7 50.1 1.0 O6 A:DG12 2.7 51.6 1.0 O6 A:DG17 2.7 47.0 1.0 O6 A:DG24 2.7 61.9 1.0 O6 A:DG23 2.8 55.9 1.0 K A:K104 3.2 77.4 1.0 K A:K102 3.3 54.5 1.0 C6 A:DG5 3.5 62.1 1.0 C6 A:DG6 3.5 66.8 1.0 C6 A:DG11 3.6 64.1 1.0 C6 A:DG23 3.6 52.5 1.0 C6 A:DG18 3.6 56.0 1.0 C6 A:DG12 3.6 60.4 1.0 C6 A:DG17 3.6 59.0 1.0 C6 A:DG24 3.7 52.2 1.0 N1 A:DG5 3.7 51.5 1.0 N1 A:DG6 3.8 58.1 1.0 N1 A:DG12 3.8 59.9 1.0 N1 A:DG11 3.9 51.0 1.0 N1 A:DG23 3.9 54.5 1.0 N1 A:DG18 3.9 57.4 1.0 N1 A:DG24 4.0 51.2 1.0 N1 A:DG17 4.0 54.4 1.0 C5 A:DG5 4.7 57.8 1.0 C5 A:DG23 4.8 56.8 1.0 C5 A:DG6 4.8 60.6 1.0 C5 A:DG11 4.8 54.1 1.0 C5 A:DG17 4.8 59.4 1.0 C5 A:DG18 4.9 55.4 1.0 C5 A:DG12 4.9 57.2 1.0 C5 A:DG24 5.0 61.2 1.0 C2 A:DG5 5.0 65.0 1.0

Potassium binding site 4 out of 4 in the Crystal Structure of A Four-Tetrad, Parallel, and K+ Stabilized Tetrahymena Thermophila Telomeric G-Quadruplex


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 4 of Crystal Structure of A Four-Tetrad, Parallel, and K+ Stabilized Tetrahymena Thermophila Telomeric G-Quadruplex within 5.0Å range: probe atom residue distance (Å) B Occ A:K104 b:77.4 occ:1.00 O6 A:DG13 2.6 49.9 1.0 O6 A:DG19 2.6 55.6 1.0 O6 A:DG25 2.7 62.6 1.0 O6 A:DG7 2.7 55.3 1.0 O6 A:DG6 2.9 55.0 1.0 O6 A:DG12 2.9 51.6 1.0 O6 A:DG18 2.9 51.9 1.0 O6 A:DG24 2.9 61.9 1.0 K A:K103 3.2 56.3 1.0 O A:HOH203 3.2 58.7 1.0 C6 A:DG13 3.5 61.1 1.0 C6 A:DG19 3.5 60.4 1.0 C6 A:DG7 3.6 66.5 1.0 C6 A:DG25 3.6 69.7 1.0 C6 A:DG12 3.7 60.4 1.0 C6 A:DG6 3.7 66.8 1.0 C6 A:DG24 3.7 52.2 1.0 C6 A:DG18 3.7 56.0 1.0 N1 A:DG13 3.8 58.5 1.0 N1 A:DG19 3.8 64.1 1.0 N1 A:DG12 3.9 59.9 1.0 N1 A:DG6 3.9 58.1 1.0 N1 A:DG25 3.9 66.0 1.0 N1 A:DG7 3.9 54.8 1.0 N1 A:DG24 4.0 51.2 1.0 N1 A:DG18 4.0 57.4 1.0 C5 A:DG13 4.8 65.7 1.0 C5 A:DG19 4.8 61.1 1.0 C5 A:DG12 4.9 57.2 1.0 C5 A:DG24 4.9 61.2 1.0 C5 A:DG7 4.9 56.7 1.0 C5 A:DG6 4.9 60.6 1.0 C5 A:DG18 4.9 55.4 1.0 C5 A:DG25 5.0 66.3 1.0

D.Beseiso, S.E.Mccarthy, J.Miao, E.P.Gallagher, E.V.Chen. Biophysical Characterization and the X-Ray Crystal Structures of G-Quadruplex Tetrahymena Thermophila Sequences in Complex with N-Methyl Mesoporphyrin IX To Be Published.